COVID-19 Research

[last updated November 4, 2020]

[Pg 1: Intro to How Covid-19 attacks, inflammation, immune health]
[Pg 2: Nutrition & Herbal Info]
[Pg 3: Exercise and Immunity]
[Pg 4: Sleep for Protection]
[Pg 5: Stress, anxiety, and mood]

[Pg 6: Bottom Line – What You Can Do]
[Pg 7: Sources and citations]

On October 25th, White House Chief of Staff Mark Meadows states, “We are not going to control the pandemic… What we need to do is make sure that we have the proper mitigation factors, whether it’s therapies or vaccines or treatments to make sure that people don’t die from this.” That is inline with what top infectious specialists, the CDC, and Public Health leaders in Ohio have been saying since April. That “it’s when, not if” you will get infected. So instead of just sitting back, hoping social distancing and hand washing keeps you out of the battle, start preparing your body now for the fire that is all but inevitable within the next few weeks, and take control. Become empowered; be proactive – there ARE things you can do.

“We don’t necessarily die by having the virus in us, we die by our immune response’s over-reaction to the virus.”

–Dr Todd Lepine

ABOUT COVID-19 AND WHAT IT DOES TO YOU

INFLAMMATION IN THE LUNGS

The coronavirus produces a protein that kicks off this domino-chain reaction of inflammation in the body. While it was first described as a virus that attacks the lungs, we’re now seeing systemic inflammation in various parts of the body including the G.I system. In children, it generally being termed Multisystem Inflammatory Syndrome in Children (MIS-C). But the premise is the same… rampant inflammation damaging the body.

But let’s look at the lungs first:

The virus triggers NLRP3 inflammasomes (fancy name for chemicals that cause internal damage in your body) which then triggers  the specific inflammatory agents that perpetuation more inflammation. Some of these agent IL-1β (Interleukin 1β, a pro-inflammatory cytokine). So the virus triggers an inflammatory agent, which triggers more inflammation.

This cascade of inflammatory chemicals targets the thin membrane where your lungs and blood normally exchange oxygen and CO2, thickening the tissues and making the exchange difficult.  All of this uncontrolled progressive inflammation continues, and the diminished gaseous exchange leads to hypoxemia (below normal levels of oxygen in the body) and damages alveoli in the lungs. Patients often develop Acute Respiratory Distress Syndrome/Acute Lung Injury (ARDS/ALI). 

When you have the flu and feel “run over by a truck,” that is usually the result of excessive cytokines and inflammation. COVID-19 is similar.

What that means: the virus causes your body to release a host of chemicals that cause inflammation in the body. The inflammation seems to target the lungs in many patients, thickening up membranes there. This makes it harder to get oxygen from your lungs into your blood, and the CO2 back out – so breathing becomes more rapid and forced. This all results in shortness of breath and often an elevated heart rate.  [this is explained in a Facebook video here]. You need to reduce inflammation in your body now, and boost your immune system to prepare for anti-inflammatory protection later.

COVID-19 and GUT HEALTH

More recent research shows that the coronavirus is also very dominant in the GI (gastrointestinal) tract.

Digestive symptoms (such as nausea, vomiting, abdominal pain, or diarrhea) were tied to worse COVID-19 hospitalization outcomes: “Whereas 60% of patients without digestive symptoms recovered and were discharged, only 34.3% of the patients with digestive symptoms recovered.” The virus seems to be able to get into the GI tract; a strong and healthy gut may have a better likelihood of protecting your body from this invader, as your GI tract is one of the first lines of defense, as well as the home to much of your immune system.

What that means: in addition to inflammation in the lungs, many patients seem to have their gut lining attacked. The gut is one of the key aspects of health and immune protection. A damaged gut is often at the root of many other health problems. So if your gut is already weak, and gets attacked by the virus, it is a damaging circle that sets you up for more health problems later in life. Diabetes, autoimmune disorders, bone and joint problems, cardiovascular disease and more all have links to leaky gut and inflammation. You need to strengthen your gut health now to build better defenses and minimize your risks.

CO-MORBIDITY AND OTHER DISEASE STATES

“Today, a large percentage of the world’s population is either elderly and/or living with one or more chronic medical conditions [such as heart disease, obesity, asthma, chronic obstructive pulmonary disease (COPD), and/or diabetes mellitus]. The number of immunosuppressed individuals (due to untreated HIV infection, transplantation or/and chemotherapy) is also increasing. This changing population demographic is of significance as each one of these host factors is known to increase the severity of even mild influenza virus infections.”

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.

%d bloggers like this: